Tacrolimus [ 104987-11-3 ]
- Appearance
- White or off-white crystalline powder
- Melting Point
- 113-115 ( ℃ )
- Boiling Point
- 481 ( ℃ )
| mp | 113-115°C |
| storage temp. | −20°C |
| solubility | DMSO: >3 mg/mL |
| form | solid |
| color | white |
| Chemical Properties | White Crystalline Solid |
| Usage | An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca |