Fludarabine [ 21679-14-1 ]
- Appearance
- white solid
- Melting Point
- 265-268 ( ℃ )
- Boiling Point
- 405.8 ( ℃ )
Purity: 98%, from ethanol - water crystallization, melting point ℃ 260. [alpha] an e19 for + 17 ° C = plus or minus 2.5 ° (0.1, ethanol). UV maximum absorption (Ph value 1, Ph 7, Ph value 262,261,262 nm (13) : 13200,14800 search-evade antagonistic, 15,000). Soluble in water and organic solvents. 5 '- single phosphate fludarabine (5' - Fiudarabine Monophosphate) : C10Hl3FN5O7P. [75607-67-9]. Soluble in water. The yankees phosphate in blood was quickly opened, the remaining 2 - fluorine o sugar adenosine (Fara - A) is entering cells, and be become to be active metabolite phosphorylation Farar - ATP and play A role. Used for chronic lymphocytic leukaemia.