Probenecid [ 57-66-9 ]

Soluble in acetone, slightly soluble in alcohol or chloroform, hardly soluble in water. Soluble in dilute sodium hydroxide solution, in dilute acids almost insoluble. Odurless, taste slightly bitter.
Use gout drug resistance. The goods for organic acid, fat-soluble strong, since renal tubular secretion eduction, and easy to be back to absorb. Therefore, in the presence of Kuai propylene sulfonylureas in some organic acids in renal tubular operation will be restrained, reduce other organic acid excretion. So for the treatment of chronic gout, safe and effective. For acute gout of pain and inflammation without effect, does not apply to acute gout.
mp | 194-196°C |
Water Solubility | <0.1 g/100 mL at 20 ºC |
Merck | 14,7754 |
Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |