Captopril [ 62571-86-2 ]

Purity: 99%, white white crystall powder, with similar characteristics of garlic smell flavor salty. Soluble in methanol, ethanol, acetone, methylene chloride or chloroform, soluble in water, insoluble in ether or hexane. It has two kinds of crystal shape, for homogeneous different crystals, melting point 106 ℃ (stable type) and melting point 84 ~ 86 ℃ (unstable type), 87 ~ 88 ℃ or melting point, then curing, second melting point ℃ 104 105. [alpha] D20-126 ° ~ - 132 ° (20mg this product soluble in 1ml ethanol). PKl 3.7, Pk2 9.8. Acute toxicity LD50 mice (mg/kg) : 1040 intravenous, 6,000 oral. Captopril as antihypertensive drugs to multiple types of hypertension, are obviously anti-hypertensie, can improve congestive heart failure patients with heart function. Mice intravenous LD50 for 1040mg/kg, oral LD50 for 6000mg/kg. Used to treat hypertension and heart failure